Ordering Recommendation

May be used as a marker of membrane permeability in urine or as an indirect marker for liver fibrosis.

Mnemonic

A2M

Methodology

Quantitative Nephelometry

Performed

Sun-Sat

Reported

1-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

CSF. Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 7 days; Frozen: 3 months (if frozen within 24 hours; avoid repeated freeze/thaw cycles)

Reference Interval

131-293 mg/dL

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

83883

Components

Component Test Code* Component Chart Name LOINC
0050005 Alpha-2-Macroglobulin 29944-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • a2-macroglobulin
  • A2M/a2M
  • AMG, macroglobulin
  • Macroglobulin, Alpha-2
Alpha-2-Macroglobulin