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Immunohistochemistry Stain Form Recommended (ARUP form #32978)

Ordering Recommendation

Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Tumor tissue.

Specimen Preparation

Formalin fix (10 percent neutral buffered formalin is preferred) and paraffin embed specimen. Protect paraffin block and / or slides from excessive heat. Transport tissue block or 5 unstained (3-5 micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min. 3 slides).If sending precut slides, do not oven bake.

Storage/Transport Temperature

Room temperature or refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Paraffin block with no tumor tissue remaining. Specimens fixed in any fixative other than 10 percent neutral buffered formalin. Decalcified specimens.

Remarks

This test code includes pathologist interpretation. Include surgical pathology report. IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services at (800) 522-2787.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.

Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Methodology

Immunohistochemistry

Performed

Mon-Fri

Reported

1-5 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

FDA

Note

This test code includes pathologist interpretation of results. Include surgical pathology report with specimen submitted for testing. Indicate tissue site on requisition.

Hotline History

N/A

CPT Codes

88360

Components

Component Test Code* Component Chart Name LOINC
0049244 Fixative Used
0049246 Time from Bx to Fixative
0049247 Duration of Fixation
0049252 p53 Percent of Tumor Cells Staining 31149-8
2004523 p53 Reference Number 94736-6
3005643 Sample Adequacy
3005652 P53 Tissue Source 31208-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • p53 IHC
  • p53 IHC with interpretation
  • p53 immunostaining
  • p53 immunostaining with interpretation
  • Tumor Protein 53
p53 with Interpretation by Immunohistochemistry