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p53 with Interpretation by Immunohistochemistry
Ordering Recommendation
Refer to ARUP Immunohistochemistry Stain Offerings brochure at www.aruplab.com/ap/resources.
New York DOH Approval Status
Specimen Required
Tumor tissue.
Formalin fix (10 percent neutral buffered formalin is preferred) and paraffin embed specimen. Protect paraffin block and / or slides from excessive heat. Transport tissue block or 5 unstained (3-5 micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min. 3 slides).If sending precut slides, do not oven bake.
Room temperature or refrigerated. Ship in cooled container during summer months.
Paraffin block with no tumor tissue remaining. Specimens fixed in any fixative other than 10 percent neutral buffered formalin. Decalcified specimens.
This test code includes pathologist interpretation. Include surgical pathology report. IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services at (800) 522-2787.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Methodology
Immunohistochemistry
Performed
Mon-Fri
Reported
1-5 days
Reference Interval
Interpretive Data
Refer to report.
FDA
Note
This test code includes pathologist interpretation of results. Include surgical pathology report with specimen submitted for testing. Indicate tissue site on requisition.
Hotline History
CPT Codes
88360
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0049244 | Fixative Used | |
| 0049246 | Time from Bx to Fixative | |
| 0049247 | Duration of Fixation | |
| 0049252 | p53 Percent of Tumor Cells Staining | 31149-8 |
| 2004523 | p53 Reference Number | 94736-6 |
| 3005643 | Sample Adequacy | |
| 3005652 | P53 Tissue Source | 31208-2 |
Aliases
- p53 IHC
- p53 IHC with interpretation
- p53 immunostaining
- p53 immunostaining with interpretation
- Tumor Protein 53
