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Time Sensitive
Ordering Recommendation

Determine myeloid lineage in AML per WHO classification. Less sensitive and specific than flow cytometry immunophenotype.

Mnemonic
MY PEROX
Methodology

Cytochemical Stain

Performed

Mon-Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or green (sodium or lithium heparin) or heparinized aspirate of bone marrow.

Specimen Preparation

Transport 6 unfixed, air-dried, and unstained push smears AND 5 mL whole blood (smears should be made from the blood submitted). OR 6 unfixed, air-dried, and unstained bone marrow aspirate smears.

Storage/Transport Temperature

Room temperature. Testing must be performed within 48 hours of collection.

Unacceptable Conditions

Frozen specimens. Peripheral blood smears older than one week. Anticoagulated blood or bone marrow sent without well-prepared unfixed smears if greater than 48 hours old.

Remarks
Stability

Ambient: 24 hours; Refrigerated: Unacceptable; Frozen: Unacceptable

Reference Interval
Interpretive Data

Refer to report.

Compliance Category

Standard

Note
Hotline History
N/A
CPT Codes

88319

Components
Component Test Code* Component Chart Name LOINC
0049030 Myeloperoxidase Stain 32817-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • MPO
  • MPO Stain
  • Peroxidase Stain
Myeloperoxidase Stain