Determine myeloid lineage in AML per WHO classification. Less sensitive and specific than flow cytometry immunophenotype.
Lavender (EDTA) or green (sodium or lithium heparin) or heparinized aspirate of bone marrow.
Transport 6 unfixed, air-dried, and unstained push smears AND 5 mL whole blood (smears should be made from the blood submitted). OR 6 unfixed, air-dried, and unstained bone marrow aspirate smears.
Room temperature. Testing must be performed within 48 hours of collection.
Frozen specimens. Peripheral blood smears older than one week. Anticoagulated blood or bone marrow sent without well-prepared unfixed smears if greater than 48 hours old.
Ambient: 24 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Refer to report.
|Component Test Code*||Component Chart Name||LOINC|
- MPO Stain
- Peroxidase Stain