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Leukocyte Alkaline Phosphatase
Copy Utility
Ordering Recommendation
Aid in differential diagnosis of neutrophilia, including chronic myeloid leukemia (CML) and leukemoid reaction.
Mnemonic
Methodology
Cytochemical Stain
Performed
Mon-Fri
Reported
1-5 days
New York DOH Approval Status
Specimen Required
Green (sodium or lithium heparin).
Protect both smears and whole blood from light and pack accordingly to avoid breakage. Transport 5 mL whole blood (Min: 1 mL) AND 6 unfixed, well-prepared smears (Min: 6 smears)
Room temperature. Send Sunday through Thursday only. Whole blood must be received within 24 hours of collection; smears must be made within 24 hours of collection and received within 7 days of collection.
Specimens collected in EDTA. Poorly prepared smears (too thick or no feather edge). Broken or fixed smears. Specimens that have been spun. Smears made from anything other than heparin. Smears made from blood older than 24 hours. Whole blood not protected from light. Smears not protected from light.
Further information on how to make an adequate smear can be found in the following instructional video: https://www.youtube.com/watch?v=ca3NwrlpS40&feature=youtube
Blood: Ambient: 24 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Unfixed Smears: Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable
Reference Interval
Female: 33-149 (no units)
Male: 22-124 (no units)
Interpretive Data
Refer to Report
Standard
Note
Hotline History
CPT Codes
85540
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0049000 | Leukocyte Alkaline Phosphatase | 4659-9 |
Aliases
- LAP
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