Ordering Recommendation

Recommended panel for the initial workup of suspected von Willebrand disease.

Mnemonic

VW PANEL

Methodology

Electromagnetic Mechanical Clot Detection/Platelet Agglutination/Microlatex Particle-Mediated Immunoassay

Performed

Mon-Sat

Reported

1-3 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer 3 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum, EDTA plasma, clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20 °C: 3 months; Frozen at -70°C: 6 months

Reference Interval

Test Number
Components
Reference Interval
  Factor VIII, Activity
Age
Reference Interval (%)
0-6 years 56-191
7-9 years 76-199
10-11 years 80-209
12-13 years 72-198
14-15 years 69-237
16-17 years 63-221
18 years and older 56-191

  von Willebrand Factor, Activity (RCF)
Age
Reference Interval (%)
0-6 years 51-215
7-9 years 52-176
10-11 years 60-195
12-13 years 50-184
14-15 years 50-203
16-17 years 49-204
18 years and older 51-215

  von Willebrand Factor, Antigen
Age
Reference Interval (%)
0-6 years 52-214
7-9 years 62-180
10-11 years 63-189
12-13 years 60-189
14-15 years 57-199
16-17 years 50-205
18 years and older 52-214

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

85240; 85246; 85245

Components

Component Test Code* Component Chart Name LOINC
0030095 Factor VIII, Activity 3209-4
0030250 von Willebrand Factor, Activity (RCF) 6014-5
0030285 von Willebrand Factor, Antigen 27816-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • F8 Activity
  • Factor VIII activity
  • Factor VIII Studies
  • von Willebrand Factor Panel
  • von Willebrand Factor, Activity; RCF
  • von Willebrand Factor, Antgien
  • vWF Ag
  • vWF Panel
von Willebrand Panel