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Factor II, Activity (Prothrombin)
0030007
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Ordering Recommendation
Evaluate for possible factor II deficiency. For prothrombin variant testing (inherited thrombotic risk factor), order Prothrombin (F2) c.*97G>A (G20210A) Pathogenic Variant (0056060).
Mnemonic
F2
Methodology
Electromagnetic Mechanical Clot Detection
Performed
Mon-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Specimen Preparation
Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions
Serum, EDTA plasma, clotted or hemolyzed specimens.
Remarks
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
Reference Interval
| Age | Reference Interval | Age | Reference Interval |
|---|---|---|---|
| 1-4 days | 26-70% | 7-9 years | 78-125% |
| 5-29 days | 33-93% | 10-11 years | 78-120% |
| 30-89 day | 34-102% | 12-13 years | 72-123% |
| 90-179 days | 45-105% | 14-15 years | 75-135% |
| 180-364 days | 60-116% | 16-17 years | 77-130% |
| 1-5 years | 71-116% | 18 years and older | 86-150% |
| 6 years | 67-107% |
Interpretive Data
Compliance Category
Standard
Note
Do not order for prothrombin mutation.
Hotline History
N/A
CPT Codes
85210
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0030007 | Factor II, Activity (Prothrombin) | 3289-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Common Pathway Proteins, Factor II
- FACTOR II ACTIVITY
- Factor II, Plasma
- Prothrombin
Factor II, Activity (Prothrombin)
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