Factor II, Activity (Prothrombin)

0030007
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Ordering Recommendation

Evaluate for possible factor II deficiency. For prothrombin variant testing (inherited thrombotic risk factor), order Prothrombin (F2) c.*97G>A (G20210A) Pathogenic Variant (0056060).

Mnemonic

F2

Methodology

Electromagnetic Mechanical Clot Detection

Performed

Mon-Sat

Reported

1-3 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum, EDTA plasma, clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

Age Reference Interval Age Reference Interval
1-4 days 26-70% 7-9 years 78-125%
5-29 days 33-93% 10-11 years 78-120%
30-89 day 34-102% 12-13 years 72-123%
90-179 days 45-105% 14-15 years 75-135%
180-364 days 60-116% 16-17 years 77-130%
1-5 years 71-116% 18 years and older 86-150%
6 years 67-107%

Interpretive Data



Compliance Category

Standard

Note

Do not order for prothrombin mutation.

Hotline History

N/A

CPT Codes

85210

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Components

Component Test Code* Component Chart Name LOINC
0030007 Factor II, Activity (Prothrombin) 3289-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Coagulation Factor II Activity Assay, Plasma
  • Common Pathway Proteins, Factor II
  • FACTOR II ACTIVITY
  • Factor II, Plasma
  • Prothrombin
Factor II, Activity (Prothrombin)