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0030007
Factor II, Activity (Prothrombin)
F2
Ordering Recommendation
Evaluate for possible factor II deficiency. For prothrombin variant testing (inherited thrombotic risk factor), order Prothrombin (F2) c.*97G>A (G20210A) Pathogenic Variant (0056060).
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Specimen Preparation
Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions
Serum, EDTA plasma, clotted or hemolyzed specimens.
Remarks
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
Methodology
Electromagnetic Mechanical Clot Detection
Performed
Mon-Sat
Reported
1-3 days
Reference Interval
| Age | Reference Interval | Age | Reference Interval |
|---|---|---|---|
| 1-4 days | 26-70% | 7-9 years | 78-125% |
| 5-29 days | 33-93% | 10-11 years | 78-120% |
| 30-89 day | 34-102% | 12-13 years | 72-123% |
| 90-179 days | 45-105% | 14-15 years | 75-135% |
| 180-364 days | 60-116% | 16-17 years | 77-130% |
| 1-5 years | 71-116% | 18 years and older | 86-150% |
| 6 years | 67-107% |
Interpretive Data
Compliance Category
Standard
Note
Do not order for prothrombin mutation.
Hotline History
N/A
CPT Codes
85210
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0030007 | Factor II, Activity (Prothrombin) | 3289-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Prothrombin
- Common Pathway Proteins, Factor II
- FACTOR II ACTIVITY
- Factor II, Plasma
Factor II, Activity (Prothrombin)
