Ordering Recommendation

Evaluate for possible factor II deficiency. For prothrombin variant testing (inherited thrombotic risk factor), order Prothrombin (F2) c.*97G>A (G20210A) Pathogenic Variant (0056060).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum, EDTA plasma, clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 2 weeks

Methodology

Electromagnetic Mechanical Clot Detection

Performed

Mon-Sat

Reported

1-3 days

Reference Interval

Age Reference Interval Age Reference Interval
1-4 days 26-70% 7-9 years 78-125%
5-29 days 33-93% 10-11 years 78-120%
30-89 day 34-102% 12-13 years 72-123%
90-179 days 45-105% 14-15 years 75-135%
180-364 days 60-116% 16-17 years 77-130%
1-5 years 71-116% 18 years and older 86-150%
6 years 67-107%

Interpretive Data



Compliance Category

Standard

Note

Do not order for prothrombin mutation.

Hotline History

N/A

CPT Codes

85210

Components

Component Test Code* Component Chart Name LOINC
0030007 Factor II, Activity (Prothrombin) 3289-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Common Pathway Proteins, Factor II
  • FACTOR II ACTIVITY
  • Factor II, Plasma
  • Prothrombin
Factor II, Activity (Prothrombin)