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Alkaline Phosphatase Isoenzymes, Serum or Plasma
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Use when total alkaline phosphatase activity is elevated to determine amounts contributed by bone and liver isoenzymes.
Quantitative Heat Inactivation/Enzymatic
Sun-Sat
1-4 days
Serum Separator Tube (SST) or Green (Sodium or Lithium Heparin).
Allow serum specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube and refrigerate or freeze immediately. (Min: 1 mL)
Refrigerated.
Specimens collected in EDTA, sodium fluoride, sodium citrate, or potassium oxalate. Grossly hemolyzed or lipemic specimens.
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 2 months
| Test Number |
Components |
||
|---|---|---|---|
| 0020005 | Alkaline Phosphatase, Serum or Plasma | Male 0-30 days: 60-320 U/L 1-11 months: 70-350 U/L 1-3 years: 125-320 U/L 4-6 years: 150-370 U/L 7-9 years: 150-440 U/L 10-11 years: 150-470 U/L 12-13 years: 160-500 U/L 14-15 years: 130-530 U/L 16-19 years: 60-270 U/L 20 years and older: 40-120 U/L |
Female 0-30 days: 60-320 U/L 1-11 months: 70-350 U/L 1-3 years: 125-320 U/L 4-6 years: 150-370 U/L 7-9 years: 150-440 U/L 10-11 years: 150-530 U/L 12-13 years: 110-525 U/L 14-15 years: 55-305 U/L 16-19 years: 40-120 U/L 20 years and older: 40-120 U/L |
| Bone | Male 1-6 years: 0-208 U/L 7-9 years: 0-264 U/L 10-15 years: 0-340 U/L 16-19 years: 0-165 U/L 20 years and older: 0-55 U/L |
Female 1-6 years: 0-189 U/L 7-9 years: 0-246 U/L 10-13 years: 0-340 U/L 14-15 years: 0-91 U/L 16 years and older: 0-55 U/L |
|
| Liver | Male 1-6 years: 0-145 U/L 7-11 years: 0-182 U/L 12-15 years: 0-226 U/L 16-19 years: 0-114 U/L 20 years and older: 0-94 U/L |
Female 1-9 years: 0-148 U/L 10-15 years: 0-162 U/L 16 years and older: 0-94 U/L |
Bone Specific Alkaline Phosphatase (0070053) and 5'Nucleotidase (0080235) may be useful in identifying disorders of bone and liver, respectively.
FDA
The presence of heat-stable isoenzymes (i.e., germ cell and placental) will be detected but their activities cannot be differentiated from the liver isoenzyme.
84075; 84080
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020005 | Alkaline Phosphatase | 6768-6 |
| 0021006 | Alk-Phosphatase Other Calc | 33421-9 |
| 0021011 | Alk-Phosphatase Bone Calc | 1777-2 |
| 0021016 | Alk-Phosphatase Liver Calc | 1779-8 |
- ALK PHOS
- Alkaline Phosphatase
- Alkaline Phosphatase Isoenzymes by Heat Fractionation
- Alkp
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