Ordering Recommendation

May use to monitor kidney stone formation. Panel includes calcium, citric acid, creatinine, oxalate, and uric acid. Preferred test is Supersaturation Profile, Urine (2008771) or Calculi Risk Assessment, Urine (2008708).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

24-hour urine. Refrigerate during collection.

Specimen Preparation

Thoroughly mix entire collection (24-hour) in one container. Transport four separate 4 mL aliquots of urine using Calculi Risk/Supersaturation Urine Collection Kit (ARUP supply# 46007). Available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787. Do not exceed 4 mL in tubes.
Aliquot according to the following specifications:
1st aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately.
2nd aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately.
3rd aliquot (pH 9): Transfer 4 mL urine into a Sodium Carbonate Tube. (Min: 4 mL) Mix well. Freeze immediately.
4th aliquot: Transfer 4 mL urine into an Unpreserved Tube. (Min: 4 mL) Freeze immediately.
                If collection kit is unavailable, transport four 4 mL unadjusted aliquots of urine.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions
Remarks

Record total volume and collection time interval on transport tube and test request form.

Stability

Ambient: Unacceptable; Refrigerated: Unacceptable Frozen: 2 weeks

Methodology

Quantitative Spectrophotometry/Quantitative Enzymatic Assay

Performed

Mon-Fri

Reported

1-6 days

Reference Interval

Test Number
Components
Reference Interval
  Calcium, Urine - per 24h
Diet
Reference Interval (mg/d)
Calcium-free diet 5-40
Low calcium diet (less than 800 mg/d) 50-150
Average calcium diet (about 800 mg/d) 100-250
High calcium diet (greater than 800 mg/d) > 250

  Creatinine, Urine - per 24h
Age
Male (mg/d)
Female (mg/d)
3-8 years 140-700 140-700
9-12 years 300-1300 300-1300
13-17 years 500-2300 400-1600
18-50 years 1000-2500 700-1600
51-80 years 800-2100 500-1400
81 years and older 600-2000 400-1300

  Uric Acid, Urine - per 24h 250-750 mg/d
  Citric Acid, Urine - per 24h 18 years and older: 320-1240 mg/d
  Oxalate, Urine - per 24h
Age
Male (mg/d)
Female (mg/d)
0-12 years 7-31 7-31
13 years and older 16-49 13-40

Interpretive Data

Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

82507; 83945; 84560; 82340

Components

Component Test Code* Component Chart Name LOINC
0020205 Calcium, Urine - per volume 17862-4
0020206 Calcium, Urine - per 24h 6874-2
0020207 Creatinine, Urine - per volume 2161-8
0020208 Creatinine, Urine - per 24h 2162-6
0020218 Uric Acid, Urine - per volume 3086-6
0020219 Uric Acid, Urine - per 24h 3087-4
0020242 Citric Acid, Urine - per 24h 6687-8
0020243 Citric Acid, Urine - per volume 2128-7
0020255 Oxalate, Urine - per 24h 2701-1
0020484 Oxalate, Urine - per volume 2700-3
0097110 Total Volume 19153-6
0097111 Hours Collected 30211-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Renal Stone Risk Panel
Kidney Stone Risk Panel, Urine