Macroprolactin

0020765
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Example Reports
High
Low
Normal

Ordering Recommendation

Mnemonic

MACROPRO

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube or plasma separator tube. Also acceptable: Lithium heparin or EDTA plasma.

Specimen Preparation

Allow specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 7 days; Frozen: 1 month

Reference Interval

Effective August 16, 2021

Test Number
 Components
 Reference Interval
0070115 Prolactin
Prolactin
Male
 Female
1-9 years 2.1-17.7 ng/mL 2.1-17.7 ng/mL
10 years and older 2.1-17.7 ng/mL 2.8-29.2 ng/mL

  Monomeric Prolactin
Age Male Female
1-9 years 2.1-13.3 ng/mL 2.1-13.3 ng/mL
10 years and older 2.1-13.3 ng/mL 2.8-19.5 ng/mL

Monomeric Prolactin Percent Greater than 50%

Interpretive Data

If the % Monomeric Prolactin is 40-50%, then the result is indeterminate for macroprolactin.  If the % Monomeric Prolactin is less than 40%, then this indicates the presence of macroprolactin.  A Monomeric Prolactin result above the upper reference limit is consistent with hyperprolactinemia.

Monomeric Prolactin was determined by PEG precipitation.  Macroprolactin is precipitated by PEG and is not measured.

Compliance Category

FDA

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/16/2021
X
X
N/A

CPT Codes

84146 x2

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Components

Component Test Code* Component Chart Name LOINC
0020766 Monomeric Prolactin 42607-2
0020767 Monomeric Prolactin Percent 50366-4
0070115 Prolactin 20568-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Macroprolactin by PEG
  • Macroprolactin, Serum
  • PRL (Prolactin)
  • Prolactin (PRL)
  • Prolactin, Macro
Macroprolactin