Ordering Recommendation

Use with FNA biopsy of thyroid nodules to diagnose benign or malignant nonmedullary thyroid nodules.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Fine needle aspiration in saline.

Specimen Preparation

Centrifuge to remove cellular material. Specimen must be non-viscous and free of particulate matter. Transfer 0.5 mL saline needle rinse to an ARUP Standard Transport Tube. (Min: 0.5 mL) Also acceptable: Heparinized specimens.

Storage/Transport Temperature


Unacceptable Conditions

Specimen types other than those listed. Specimens containing EDTA. Viscous specimens.


Indicate source on test request form.


Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months


Quantitative Chemiluminescent Immunoassay




Within 24 hours

Reference Interval

By report

Interpretive Data

Thyroglobulin (Tg) is measured by the Beckman Coulter Access method. Results obtained with different assay methods or kits cannot be used interchangeably. The Tg result, regardless of concentration, should not be interpreted as absolute evidence for the presence or absence of papillary or follicular thyroid cancer. This test is FDA cleared but is not labeled for use with FNA fluid.

The performance characteristics of this test were determined by ARUP.

Normal values are less than 10 ng/mL (Baloch ZW et al., CytoJournal 2008, 5:1).

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA-certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0020754 Thyroglobulin, Fine Needle Aspiration 53922-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • FNA TG
Thyroglobulin, Fine Needle Aspiration (FNA)