Ordering Recommendation
Mnemonic
OSTEO NMID
Methodology

Quantitative Electrochemiluminescent Immunoassay

Performed

Tue-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Allow serum tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 3 months

Reference Interval
Age
Male
Female
6 months-6 years 39-121 ng/mL 44-130 ng/mL
7-9 years 66-182 ng/mL 73-206 ng/mL
10-12 years 85-232 ng/mL 77-262 ng/mL
13-15 years 70-336 ng/mL 33-222 ng/mL
16-17 years 43-237 ng/mL 24-99 ng/mL
18 years and older 11-50 ng/mL 11-50 ng/mL

Interpretive Data

In patients with renal failure the osteocalcin result can be elevated, both directly, due to impaired clearance, and indirectly, due to renal osteodystrophy.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

83937

Components
Component Test Code* Component Chart Name LOINC
0020728 Osteocalcin by ECIA 2697-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • BGLAP
  • bone gamma-carboxyglutamic acid-containing protein
  • N-MID osteocalcin
  • Osteocalcin
  • Osteocalcin (OCN)
Osteocalcin by Electrochemiluminescent Immunoassay