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Osteocalcin by Electrochemiluminescent Immunoassay
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Ordering Recommendation
Mnemonic
Methodology
Quantitative Electrochemiluminescent Immunoassay
Performed
Tue-Sat
Reported
1-4 days
New York DOH Approval Status
Specimen Required
Serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Allow serum tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Frozen.
Hemolyzed specimens.
After separation from cells: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 3 months
Reference Interval
| Age |
Male |
Female |
|---|---|---|
| 6 months-6 years | 39-121 ng/mL | 44-130 ng/mL |
| 7-9 years | 66-182 ng/mL | 73-206 ng/mL |
| 10-12 years | 85-232 ng/mL | 77-262 ng/mL |
| 13-15 years | 70-336 ng/mL | 33-222 ng/mL |
| 16-17 years | 43-237 ng/mL | 24-99 ng/mL |
| 18 years and older | 11-50 ng/mL | 11-50 ng/mL |
Interpretive Data
In patients with renal failure the osteocalcin result can be elevated, both directly, due to impaired clearance, and indirectly, due to renal osteodystrophy.
FDA
Note
Hotline History
CPT Codes
83937
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020728 | Osteocalcin by ECIA | 2697-1 |
Aliases
- BGLAP
- bone gamma-carboxyglutamic acid-containing protein
- N-MID osteocalcin
- Osteocalcin
- Osteocalcin (OCN)
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