Ordering Recommendation
Mnemonic
GFRE
Methodology

Quantitative Enzymatic

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plasma separator tube or serum separator tube. Also acceptable: Lavender (EDTA).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Specimens obtained through catheters used to infuse hyperalimentation fluid. Specimens collected with potassium oxalate/sodium fluoride or sodium citrate.

Remarks

Patient age and sex are required for calculation.

Stability

After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 3 months

Reference Interval

Effective August 20, 2018
Calculated GFR - >= 60 mL/min / 1.73 square meters

Creatinine
Age
Male
Female
0-30 days 0.50-1.20 mg/dL 0.50-0.90 mg/dL
31-364 days 0.40-0.70 mg/dL 0.40-0.60 mg/dL
1-3 years 0.40-0.70 mg/dL 0.40-0.70 mg/dL
4-6 years 0.50-0.80 mg/dL 0.50-0.80 mg/dL
7-9 years 0.30-0.60 mg/dL 0.30-0.70 mg/dL
10-11 years 0.30-0.70 mg/dL 0.40-0.80 mg/dL
12-13 years 0.40-0.80 mg/dL 0.40-0.80 mg/dL
14-15 years 0.40-1.10 mg/dL 0.30-0.90 mg/dL
16-18 years 0.60-1.20 mg/dL 0.50-1.00 mg/dL
19 years and older 0.40-1.20 mg/dL 0.40-1.20 mg/dL

Interpretive Data

The CKD-EPI equation for non-African American individuals is used to calculate the estimated glomerular filtration rate (GFR). To estimate the GFR for African Americans, multiply the provided GFR result by 1.16.

The CKD-EPI equation is validated in individuals 18 years of age and older. It is less accurate in patients with extremes of muscle mass, restriction of dietary protein, ingestion of creatine, extra-renal metabolism of creatinine, or treatment with medications that affect renal tubular creatinine secretion.


GFR Categories in Chronic Kidney Disease (CKD)
GFR Category
GFR (mL/min/1.73 square meters)
Interpretation
G1 90 or greater Normal or high*
G2 60-89 Mild decrease*
G3a 45-59 Mild to moderate decrease
G3b 30-44 Moderate to severe decrease
G4 15-29 Severe decrease
G5 14 or less Kidney failure
*In the absence of evidence of kidney damage, neither GFR category G1 nor G2 fulfill the criteria for CKD (Kidney Int Suppl 2013;3:1-150)

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

82565

Components
Component Test Code* Component Chart Name LOINC
0020025 Creatinine, Serum or Plasma 2160-0
0026634 Calculated GFR 62238-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Calculated Glomerular Filtration Rate
  • cGFR
  • eGFR
  • Estimated Glomerular Filtration Rate
Glomerular Filtration Rate, Estimated