Ordering Recommendation

Use this test for patients with prolactin-secreting macroadenomas, where a high-dose hook effect is a consideration.

Mnemonic

PROLAC MAC

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube or plasma separator tube. Also acceptable: Lithium heparin or EDTA plasma).

Specimen Preparation

Allow specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube.

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks
Stability

Ambient: 8 hours; Refrigerated: 7 days; Frozen: 1 month

Reference Interval

Effective August 16, 2021

Prolactin
Age
Male
Female, nonpregnant
1-9 years 2.1-17.7 ng/mL 2.1-17.7 ng/mL
10 years and older 2.1-17.7 ng/mL 2.8-29.2 ng/mL

Interpretive Data



Compliance Category

FDA

Note

This test is intended for patients with prolactin-secreting macroadenomas, where a high-dose hook effect is a consideration. Pregnancy, lactation, and the administration of oral contraceptives can increase prolactin concentrations.

Hotline History

N/A

CPT Codes

84146

Components

Component Test Code* Component Chart Name LOINC
0020724 Prolactin, Dilution Study 20568-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Dilution for high dose hook effect
  • Macroadenoma
  • Prolactin, Dilution Study
Prolactin, Dilution Study