Ordering Recommendation

Use this test for patients with prolactin-secreting macroadenomas, where a high-dose hook effect is a consideration.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube or plasma separator tube. Also acceptable: Lithium heparin or EDTA plasma).

Specimen Preparation

Allow specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube.

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks
Stability

Ambient: 8 hours; Refrigerated: 7 days; Frozen: 1 month

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Effective August 16, 2021

Age
Male
Female, nonpregnant
1-9 years 2.1-17.7 ng/mL 2.1-17.7 ng/mL
10 years and older 2.1-17.7 ng/mL 2.8-29.2 ng/mL

Interpretive Data

Interpretive Information:

Pregnant 9.7- >200.0 ng/mL

Postmenopausal 1.8-20.3 ng/mL

Access complete set of age- and/or gender-specific reference intervals for this test in the ARUP Laboratory Test Directory (aruplab.com).

Compliance Category

FDA

Note

This test is intended for patients with prolactin-secreting macroadenomas, where a high-dose hook effect is a consideration. Pregnancy, lactation, and the administration of oral contraceptives can increase prolactin concentrations.

Hotline History

N/A

CPT Codes

84146

Components

Component Test Code* Component Chart Name LOINC
0020724 Prolactin, Dilution Study 20568-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Dilution for high dose hook effect
  • Macroadenoma
  • Prolactin, Dilution Study
Prolactin, Dilution Study