Useful as an indicator of chronic exposure to lead in the industrial setting. For a complete assessment of industrial lead exposure in adults and exposure guidance in accordance with OSHA regulations, Lead, Industrial Exposure Panel, Adults (0025016) is preferred.
New York DOH Approval Status
Lavender (EDTA), royal blue (EDTA), or tan (EDTA). Use royal blue (EDTA) tube when also testing for lead.
Transport 1 mL whole blood. (Min: 0.2 mL)
Specimens not collected in EDTA. Clotted, frozen, or hemolyzed specimens.
Ambient: 30 hours; Refrigerated: 5 weeks; Frozen: Unacceptable
|Zinc Protoporphyrin, Blood||0-40 µg/dL|
|Zinc Protoporphyrin (ZPP) WholeBld Ratio||0-69 µmol ZPP/mol heme|
For occupational exposure to lead, OSHA requires ZPP whole blood concentration to be reported in units of µg/dL. For adults, conversion of ZPP to units of µg/dL assumes a hematocrit of 45%.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Elevated ZPP results are seen in early and late iron deficiency, the anemia of chronic disease, chronic lead poisoning, and erythropoietic protoporphyria. Elevated bilirubin or riboflavin and hemolyzed, clotted, or improperly aliquoted specimens may falsely increase the ZPP concentration.
|Component Test Code*||Component Chart Name||LOINC|
|0020606||Zinc Protoporphyrin (ZPP) WholeBld Ratio||29763-0|
|0020613||Zinc Protoporphyrin, Blood||2895-1|
- ZPP/Heme Ratio