Ordering Recommendation

Useful in the assessment of recent exposure to arsenic, cadmium, mercury, and lead. For chronic exposure or the determination of arsenic species, refer to Heavy Metals Panel 4, Urine with Reflex to Arsenic Fractionation (0020572). For occupational exposure, consider Lead, Industrial, Whole Blood (0025016) and/or Cadmium Exposure Panel - OSHA (0025013).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances.  Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician), and avoid shellfish and seafood for 48 to 72 hours.

Collect

Royal blue(K2EDTA) or Royal blue (NaHep).

Specimen Preparation

Transport 3 or 6 mL whole blood in the original collection tube. (Min: 0.5 mL)

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated.

Unacceptable Conditions

Specimens collected in tubes other than Royal blue(K2EDTA) or Royal blue (NaHep). Specimens transported in containers other than Royal blue (K2EDTA) or Royal blue (NaHep). Trace Element-Free Transport Tube. Clotted specimens.

Remarks
Stability

Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Test Number
Components
Reference Interval
  Lead, Whole Blood (Venous) Less than or equal to 3.4 µg/dL
  Arsenic, Whole Blood Less than or equal to 12.0 µg/L
  Mercury, Whole Blood Less than or equal to 10.0 µg/L
  Cadmium, Whole Blood Less than or equal to 5.0 µg/L

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Mercury is volatile; concentration may decrease over time.  If the specimen is drawn and stored in the appropriate container, the arsenic, cadmium, and lead values do not change with time.

Hotline History

N/A

CPT Codes

82175; 83655; 83825; 82300

Components

Component Test Code* Component Chart Name LOINC
0020098 Lead, Whole Blood (Venous) 77307-7
0099045 Arsenic, Whole Blood 5583-0
0099305 Mercury, Whole Blood 5685-3
0099675 Cadmium, Whole Blood 5609-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Arsenic
  • Mercury
  • Lead
  • Cadmium
  • Heavy metals blood levels
  • AS blood level
  • Cd blood level
  • Pb blood level
  • Hg blood level
Heavy Metals Panel 4, Whole Blood