Ordering Recommendation

Indicates stage of infection. Use to monitor patients with chronic hepatitis B infection and known positive Hepatitis B surface antigen.

Mnemonic
HEPCHRONIC
Methodology

Qualitative Chemiluminescent Immunoassay/Qualitative Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Refer to individual components.

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 2 mL) Also acceptable: K2EDTA plasma.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Heparinized plasma. Specimens containing particulate material. Heat-inactivated, severely hemolyzed, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinitely (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0020090 Hepatitis B Virus Surface Antibody
Less than 10.00 IU/L Negative
Greater than or equal to 10.00 IU/L Positive

0020089 Hepatitis B Virus Surface Antigen with Reflex to Confirmation
Test Number
Components
Reference Interval
Hepatitis B Virus Surface Antigen Negative
0020128 Hepatitis B Virus Surface Antigen, Confirmation Refer to report

0020095 Hepatitis Be Virus Antibody Negative
0020094 Hepatitis Be Virus Antigen Negative

Interpretive Data

This panel of assays should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P). 

Compliance Category

FDA

Note

Order this panel when the patient is known to have chronic hepatitis B infection to determine the degree of infection and monitor the development of immunity. If results for HBsAg are repeatedly reactive with an index value between 1.00 and 50.00, then HBsAg Confirmation will be added. Additional charges apply.

Hotline History
N/A
CPT Codes

86317; 86707; 87340; 87350; if reflexed, add 87341

Components
Component Test Code* Component Chart Name LOINC
0020089 Hepatitis B Surface Antigen 65633-0
0020090 Hepatitis B Surface Antibody 5193-8
0020094 Hepatitis Be Antigen 13954-3
0020095 Hepatitis Be Antibody 13953-5
0020522 Chronic Hepatitis B Panel Interpretation 45159-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Chronic HBV panel
  • chronic Hep B Panel
  • Chronic Hepatitis B Panel
  • H Be Ab
  • H Be Ag
  • HBs antibody
  • HBsAg
  • Hepatitis B Immune Status Profile, Serum
  • Hepatitis B Surface Antibody
  • Hepatitis B Surface Antigen
  • Hepatitis Be Antibody
  • Hepatitis Be Antigen
Hepatitis B Virus Panel, Chronic with Reflex to HBsAg Confirmation