Creatine Kinase Isoenzymes

0020414
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Example Reports
Abnormal
Normal

Ordering Recommendation

Aid in determining the etiology of elevated total creatine kinase. Troponin I (0090613) or Troponin T (cTnT) 5th Generation (3001831) are the recommended tests for diagnosis and management of acute coronary syndrome. May aid in identifying the presence of macro creatine kinase.

Mnemonic

CKISO

Methodology

Quantitative Enzymatic/Electrophoresis

Performed

Sun-Sat

Reported

2-3 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Specimens preserved in citrate, EDTA, fluoride, heparin, or iodoacetate. Grossly hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
 Components
 Reference Interval
  CK-MM 96-100%
  CK-MB 0-4%
  CK-BB 0%
  CK-Macro Type I 0%
  CK-Macro Type II 0%
  CK Total Effective February 22, 2022
Age:
 Male:
 Female:
0-30 days
31 days-5 months
6-35 months
3-6 years
7-17 years
18 years and older:		 108-564 U/L
72-367 U/L
50-272 U/L
56-281 U/L
60-393 U/L
39-308 U/L		 108-564 U/L
72-367 U/L
38-261 U/L
40-222 U/L
46-250 U/L
26-192 U/L

Interpretive Data



Compliance Category

FDA

Note

This test will detect CK macroenzymes.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
02/22/2022
X
N/A

CPT Codes

82552; 82550

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Components

Component Test Code* Component Chart Name LOINC
0020020 CK-MM 15049-0
0020021 CK-MB 12187-1
0020022 CK-BB 15048-2
0020108 CK Total 2157-6
2001881 CK-Macro Type I 26019-0
2001882 CK-Macro Type II 26020-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • CK
  • CK Fractionation
  • CK Isoenzyme Electrophoresis
  • CK Isoenzymes
  • CK Macro
  • CK-BB
  • CK-MM
  • CKBB
  • CKMB
  • CPK
  • CPK Isoenzyme Electrophoresis
  • CPK Isoenzymes (Creatine Phosphokinase Isoenzymes)
  • Creatine Phosphokinase
  • Isoenzyme of Creatine Kinase
  • Isoenzymes, CK
  • Macro CK
  • Macro Creatine Kinase
  • Mitochondrial C
Creatine Kinase Isoenzymes