LDL Cholesterol, Direct

0020257
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Example Reports
Abnormal
Normal

Ordering Recommendation

Use to assess cardiovascular disease risk and guide therapy.

Mnemonic

LDL D

Methodology

Quantitative Detergent Solubilization/ Enzymatic

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plasma separator tube or serum separator tube. Also acceptable: Green (lithium heparin), Lavender (K2 EDTA or K3 EDTA), or Pink (K2 EDTA).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 7 days; Frozen: 12 months

Reference Interval

Age
 Desirable
 Borderline
 Higher Risk
0-19 years 109 mg/dL or less 110-129 mg/dL 130 mg/dL or greater
20 years and older 129 mg/dL or less (99 mg/dL or less if patient has CHD) 130-159 mg/dL 160 mg/dL or greater

Interpretive Data

CHD Risk Factors:                                                            
+1  Age: Men, 45 years and older                                         
                Women, 55 years and older or premature menopause without estrogen therapy                                   
+1  Family history of premature CHD                                        
+1  Current smoking                                                        
+1  Hypertension                                                           
+1  Diabetes mellitus                                                      
+1  Low HDL Cholesterol: 39 mg/dL or less                                 
 -1  High HDL Cholesterol: 60 mg/dL or greater     
                                                                              
LDL Cholesterol: Therapeutic goal                                            
99 mg/dL or less if CHD is present  (Optional 69 mg/dL or less).   
129 mg/dL or less if no CHD and two or more risk factors.                  
159 mg/dL or less if no CHD. 
(Circulation 2004; 110:227-39)

Compliance Category

FDA

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
02/22/2022
X
N/A

CPT Codes

83721

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Components

Component Test Code* Component Chart Name LOINC
0020257 LDL Cholesterol, Direct 18262-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Direct LDL
  • LDL
  • Low Density Lipoprotein
LDL Cholesterol, Direct