Ordering Recommendation

Preferred test for evaluating acute and chronic exposure to organophosphate pesticides.

Mnemonic
CHE-SCRN
Methodology

Quantitative Enzymatic

Performed

Mon-Fri

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation

DO NOT FREEZE. Do not spin down or separate. Transport 3 mL whole blood. (Min: 2 mL)

Storage/Transport Temperature

Refrigerated. Do not place whole blood directly on cool pack when shipping.

Unacceptable Conditions

Green (sodium or lithium heparin). Frozen whole blood. Hemolyzed specimens.

Remarks
Stability

Ambient: 4 hours; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval
Test Number
Components
Reference Interval
  Cholinesterase, Plasma 2.9-7.1 U/mL
  Cholinesterase, RBC 7.9-17.1 U/mL RBC
  Cholinesterase, RBC - ratio to Hb 25-52 U/g Hb
  Cholinesterase, Plasma (Ellman) 1.0-2.4 U/mL
  Cholinesterase, RBC (Ellman) 4.0-9.0 U/mL WB

Interpretive Data

Ellman Std. test results obtained using a conversion factor which standardizes to the acetylthiocholine assay at 25°C.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

82480; 82482

Components
Component Test Code* Component Chart Name LOINC
0020196 Cholinesterase, Plasma 2098-2
0020197 Cholinesterase, RBC - ratio to Hb 49231-4
0020448 Cholinesterase, RBC 2099-0
0020449 Cholinesterase, Plasma (Ellman) 2098-2
0020450 Cholinesterase, RBC (Ellman) 2099-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cholinesterase, RBC & Pseudocholinesterase
  • Pseudocholinesterase & Cholinesterase, RBC
Insecticide Exposure Panel