Ordering Recommendation

Use to assess cardiovascular disease risk and guide therapy.

Mnemonic
CH HDL
Methodology

Detergent Solubilization/Enzymatic

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plasma separator tube or serum separator tube.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month

Reference Interval

Desirable: 40-59 mg/dL

Interpretive Data

An HDL cholesterol less than 40 mg/dL is low and constitutes a coronary heart disease risk factor.  An HDL cholesterol greater than 60 mg/dL is a negative risk factor for coronary heart disease.

CHD Risk Factors
+1  Age: Men > 45
     Women > 55 or premature menopause without estrogen therapy
+1 Family history of premature CHD
+1  Current smoking
+1  Hypertension
+1  Diabetes mellitus
+1  Low HDL cholesterol: < 40 mg/dL
-1  High HDL cholesterol: ≥ 60 mg/dL

Compliance Category

FDA

Note

Assay interference (negative) may be observed when high concentrations of N-acetylcysteine (NAC) are present. Negative interference has also been reported with NAPQI (an acetaminophen metabolite), but only when concentrations are at or above those expected during acetaminophen overdose.

Hotline History
N/A
CPT Codes

83718

Components
Component Test Code* Component Chart Name LOINC
0020053 HDL Cholesterol 2085-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cholesterol
  • Cholesterol, HDL
  • HDL
  • HDL Direct
  • High Density Lipoprotein
  • High Density Lipoprotein, Cholesterol
HDL Cholesterol