Ordering Recommendation

Allergen testing for patients in Hawaii.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum Separator Tube (SST). Multiple specimen tubes should be avoided.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 4 mL serum to an ARUP Standard Transport Tube. (Min: 1.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Test Number
Components
Reference Interval
  Immunoglobulin E
Age Reference Interval (kU/L)
0-5 months 13 or less
6-12 months 34 or less
1-2 years 97 or less
3 years 199 or less
4-6 years 307 or less
7-8 years 403 or less
9-12 years 696 or less
13-15 years 629 or less
16-17 years 537 or less
18 years and older 214 or less

  Allergen, Fungi/Mold, A. alternata IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Cat Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Pigweed IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Perennial Rye IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Sagebrush/Wormwood IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, Hormodendrum IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, English Plantain IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, A. fumigatus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. pteronyssinus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. farinae IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Bermuda Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, P. notatum IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Common/Short Ragweed IgE Less than or equal to 0.34 kU/L
  Allergen, Insect, Cockroach, German IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Pine/Australian Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Eucalyptus Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Mesquite Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Bahia IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Mouse Epithelium IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, M. racemosus IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Palm/Queen Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Bayberry IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Cocklebur IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, White Mulberry Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Dog Dander IgE Less than or equal to 0.34 kU/L

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.


Reporting Range (reported in kU/L) Probability of IgE Mediated Clinical Reaction Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Compliance Category

FDA

Note

Allergens included in this panel: Alternaria alternata (tenuis), Aspergillus fumigatus, Bahia Grass, Bayberry Tree, Bermuda Grass, Cat Dander, Cocklebur, Cockroach (German), Common Short Ragweed, D. pteronyssinus (mites), D. farinae (mites), Dog Dander, English Plantain, Eucalyptus Tree, Hormodendrum (Cladosporium), Mesquite Tree, Mouse Epithelium, Mucor racemosus, Palm Tree, Penicillium notatum, Perennial Rye Grass, Pigweed, Pine/Australian Pine, Sagebrush/Wormwood, White Mulberry Tree, and IgE Serum Total.

Hotline History

N/A

CPT Codes

86003 x25; 82785

Components

Component Test Code* Component Chart Name LOINC
0050345 Immunoglobulin E 19113-0
0055001 Allergen, Fungi/Mold, A. alternata IgE 6020-2
0055006 Allergen, Animal, Cat Dander IgE 6833-8
0055025 Allergen, Weed, Pigweed IgE 7604-2
0055028 Allergen, Grass, Perennial Rye IgE 7369-2
0055029 Allergen, Weed, Sagebrush/Wormwood IgE 6286-9
0055038 Allergen, Fungi/Mold, Hormodendrum IgE 6075-6
0055049 Allergen, Weed, English Plantain IgE 6110-1
0055061 Allergen, Fungi/Mold, A. fumigatus IgE 6025-1
0055063 Allergen, Mites, D. pteronyssinus IgE 6096-2
0055064 Allergen, Mites, D. farinae IgE 6095-4
0055070 Allergen, Grass, Bermuda Grass IgE 6041-8
0055080 Allergen, Fungi/Mold, P. notatum IgE 6212-5
0055085 Allergen, Weed, Common/Short Ragweed IgE 6085-5
0055088 Allergen, Insect, Cockroach, German IgE 6078-0
0055089 Allergen, Tree, Pine/Australian Tree IgE 6032-7
0055098 Allergen, Tree, Eucalyptus Tree IgE 6113-5
0055140 Allergen, Tree, Mesquite Tree IgE 6173-9
0055151 Allergen, Grass, Bahia IgE 6034-3
0055191 Allergen, Animal, Mouse Epithelium IgE 6179-6
0055442 Allergen, Fungi/Mold, M. racemosus IgE 6182-0
0098861 Allergen, Tree, Palm/Queen Tree IgE 6222-4
0098870 Allergen, Tree, Bayberry IgE 7123-3
0099472 Allergen, Weed, Cocklebur IgE 6077-2
0099554 Allergen, Tree, White Mulberry Tree IgE 6281-0
0099568 Allergen, Animal, Dog Dander IgE 6098-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Allergen, Region 20 Respiratory Panel IgE, Hawaii