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Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen
2014694
Ordering Recommendation

Monitor engraftment of maternal T cells in patients with severe combined immunodeficiency (SCID) prior to allogenic stem cell transplantation.

Mnemonic
SCID-PRE
Methodology
Polymerase Chain Reaction/Fragment Analysis
Performed
Sun-Sat
Reported
5-9 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Buccal swab or buccal brush. 
Specimen Preparation
Collect 3-4 swab/brush samples from patient and place in dry, sterile container for transport. 
Storage/Transport Temperature
Room temperature. 
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
By report
Interpretive Data
Refer to report.

Note
To complete Maternal T Cell Engraftment in SCID testing, samples should be collected to perform the following three tests: (1) A buccal swab or brush collected from the patient for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694), used as a genetic baseline for the patient. (2) A peripheral blood sample from the biological mother for Maternal T Cell Engraftment in SCID, Maternal Specimen (ARUP test code 2014704), used as a genetic baseline for the mother. (3) A peripheral blood sample collected from the patient for Maternal T Cell Engraftment in SCID, (ARUP test code 2014699). T cells isolated from the blood sample will be genotyped for comparison to the patient and biological mother baseline genotypes. If T cell sorting is not completed on the blood sample before submission, BMT Cell Isolation (ARUP test code 2005498) will be added. Additional charges apply.
Hotline History
N/A
Components
Component Test Code*Component Chart NameLOINC
2014695Specimen, Maternal Engraftment Pre
2014696Maternal Engraftment, Pre Interp
2014697Mat Engraftment, Pre, Informative Loci
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Maternal cell engraftment
  • Maternal engraftment
  • SCID
  • SCID engraftment