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Gastrointestinal Hereditary Cancer Panel, Sequencing and Deletion/Duplication, 16 Genes
2013449
Ordering Recommendation

Confirm a diagnosis of hereditary gastrointestinal (GI) cancer in individuals with a personal or family history of GI cancer and/or polyposis.

Mnemonic
GICAN PAN
Methodology
Massively Parallel Sequencing/Exonic Oligonucleotide-based CGH Microarray/Sequencing/Multiplex Ligation-dependent Probe Amplification
Performed
Varies
Reported
10-12 weeks
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or Yellow (ACD Solution A or B). 
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
By report
Interpretive Data
Refer to report.

Compliance Statement C: The performance characteristics of this test were validated by ARUP Laboratories. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test. However, FDA approval or clearance is currently not required for clinical use of this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. ARUP is authorized under Clinical Laboratory Improvement Amendments (CLIA) and by all states to perform high-complexity testing. Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Components
Component Test Code*Component Chart NameLOINC
2010199Gastrointestinal Cancer Panel - Spcmn31208-2
2013450Gastrointestinal Cancer Panel - Interp41103-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • APC
  • BMPR1A
  • CDH1
  • Cowden syndrome
  • EPCAM
  • Familial adenomatous polyposis (FAP)
  • Hereditary Nonpolyposis Colorectal Cancer (HNPCC)
  • Juvenile polyposis
  • Lynch
  • MLH1
  • MSH2
  • MSH6
  • MUTYH
  • MUTYH-associated polyposis (MAP)
  • Paraganglioma Pheochromocytoma
  • Peutz-Jeghers
  • PMS2
  • PTEN
  • SDHB
  • SDHC
  • SDHD
  • SMAD4
  • STK11
  • TP53