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Hemoglobin S, Sickle Solubility
2013399
Ordering Recommendation

Effective test for secondary confirmation of hemoglobin (Hb) S. Not recommended for newborns <6 months due to high concentration of HbF. Confirm results with Hemoglobin Evaluation with Reflex to Electrophoresis and/or RBC Solubility (0050610). 

Mnemonic
SICKLE
Methodology
RBC Solubility
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or pink (K2EDTA). 
Specimen Preparation
Transport 5 mL whole blood. (Min: 0.2 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
Interpretive Data
Refer to report.

Components
Component Test Code*Component Chart NameLOINC
2013400Sickle Cell Solubility Result6864-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Hb S
  • Hgb S
  • Sickle Cell Anemia Screen
  • Sickle Cell Disease