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CD200 by Immunohistochemistry
2012844
Ordering Recommendation

Primarily aids the distinction between CLL/SLL and mantle cell lymphoma where CD200 is usually positive in CLL/SLL and negative in mantle cell lymphoma. CD200 is also positive in other B-cell lymphoproliferative disorders.

Mnemonic
CD200 IHC
Methodology
Immunohistochemistry
Performed
Mon-Fri
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Tissue. 
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit (recommended but not required), (ARUP supply #47808) available online through eSupply using ARUP Connect or contact ARUP Client Services at (800) 522-2787. (Min: 2 slides) If sending precut slides, do not oven bake. 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months. 
Unacceptable Conditions
Specimens submitted with non-representative tissue type. Depleted specimens. 
Remarks
 
Stability
Ambient: Indefinitely, Refrigerated: Indefinitely, Frozen: Unacceptable 
Reference Interval
Interpretive Data


Note
All stains will be handled as "Stain and Return" unless a consultation is requested. To request a consultation, submit the pathology report, all associated case materials (clinical history, blocks, slides, etc.), and the Anatomic Pathology requisition form (#32960) in place of the Immunohistochemistry Stain Form.
CPT Code(s)
88342
Components
Component Test Code*Component Chart NameLOINC
2012845CD200 Client Case or Reference Number
2012846CD200 by Immunohistochemistry
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases