Pain Management Panel, Screen with Reflex to Quantitation
Ordering Recommendation

Use for general testing in contexts of compliance and/or abuse, primarily in the pain management population. Alternative testing strategies include Pain Management Drug Panel by High-Resolution Time-of-Flight or Tandem Mass Spectrometry and Enzyme Immunoassay, Urine (2007479) and Pain Management Drug Panel with Interpretation by High-Resolution Time-of-Flight or Tandem Mass Spectrometry and Enzyme Immunoassay, Urine (2009288).

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography-Tandem Mass Spectrometry
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Random Urine. 
Specimen Preparation
Transfer 4 mL each into two (2) ARUP Standard Transport Tubes urine with no additives or preservatives. (Min: 2 mL each) 
Storage/Transport Temperature
Unacceptable Conditions
Specimens exposed to multiple freeze/thaw cycles, Pharmaceutical preparation. 
Ambient: 1 week; Refrigerated: 1 month; frozen: 3 years 
Reference Interval
Drugs covered and range of cutoff concentrations
Drugs/Drug ClassesScreen
Amphetamines300 ng/mL
Barbiturates200 ng/mL
Benzodiazepines200 ng/mL
Buprenorphine5 ng/mL
Carisoprodol100 ng/mL
Cocaine150 ng/mL
Ethyl Glucuronide500 ng/mL
Fentanyl2 ng/mL
MDMA (Ecstasy)500 ng/mL
Meperidine200 ng/mL
Methadone150 ng/mL
Opiates300 ng/mL
Oxycodone100 ng/mL
Phencyclidine25 ng/mL
Propoxyphene300 ng/mL
Tapentadol200 ng/mL
Tramadol200 ng/mL
THC (Cannabinoids)20 ng/mL
Zolpidem20 ng/mL

Interpretive Data
The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies. Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more specific technology (GC/MS and or LC MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

If the specimen screens positive, then Confirmation/Quantitation by GC/MS and/or LC-MS/MS will be added to confirm result. Additional charges apply.
Hotline History
View Hotline History
CPT Code(s)
80307; if reflexed, add 80321; 80325; 80345; 80346; 80348; 80349; 80353; 80354; 80358; 80359; 80361; 80362; 80365; 80367; 80368; 80369; 80372; 80373; 83992 (Reflexed Alt Code: G0480 )
Component Test Code*Component Chart NameLOINC
0090386Creatinine, Urine2161-8
0092191Amphetamines, Urn, Screen19348-2
0092192Cocaine, Urn, Screen19359-9
0092194Phencyclidine, Urn, Screen19661-8
0092195THC, Urn, Screen19292-2
0092196Barbiturates, Urn, Screen19276-5
0092197Benzodiazepines, Urn, Screen19284-9
0092198Propoxyphene, Urn, Screen19432-4
0092199Methadone, Urn, Screen19553-7
2005094Opiates, Urn, Screen19295-5
2005102Oxycodone/Oxymorphone, Urn, Screen58430-0
2007913Ethyl Glucuronide Screen w/Rflx, Urine58375-7
2012212Screen, Urine Interpretation54247-2
2012274Buprenorphine, Urn, Screen3415-7
2012279Carisoprodol, Urn, Screen10979-3
2012285Fentanyl, Urn, Screen11235-9
2012289Meperidine, Urn, Screen3746-5
2012295Tapentadol, Urn, Screen65807-0
2012298Tramadol, Urn, Screen19712-9
2012301Zolpidem, Urn, Screen33339-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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