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Porphobilinogen (PBG), Random Urine
2011476
Ordering Recommendation

Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.

Mnemonic
UPBGQTRAND
Methodology
Quantitative Ion Exchange Chromatography/Spectrophotometry
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Random urine. 
Specimen Preparation
Protect from light. Transfer an 8 mL aliquot from a well-mixed collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Body fluids other than urine. 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month 
Reference Interval
Components
Reference Interval
Porphobilinogen (PBG), Urine-per volume0.0-8.8 µmol/L
Porphobilinogen, Rndm Urn-ratio to CRTNo reference interval (mg/g crt)

Interpretive Data


Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attacks of other types of porphyrias associated with neurologic and/or psychiatric symptoms.
Hotline History
N/A
Components
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume2161-8
0080262Porphobilinogen (PBG), Urine -per volume2811-8
2011477Porphobilinogen, Rndm Urn-ratio to CRT13797-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • PBG, Quantitative
  • Porphobilinogen
  • Watson-Schwartz Test