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CBFB-MYH11 inv(16) Detection, Quantitative
2011114
Ordering Recommendation

For detection of CBFB-MYH11 fusion transcripts resulting from inv(16)/t(16;16) in patients with acute myeloid leukemia.

Mnemonic
INV 16 QNT
Methodology
Reverse Transcription Quantitative Polymerase Chain Reaction
Performed
RNA isolation: Sun-Sat
Assay: Varies
Reported
5-7 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or bone marrow (EDTA). 
Specimen Preparation
Transport 5 mL whole blood. (Min: 1 mL) OR Transport 3 mL bone marrow. (Min: 1 mL) Specimens must be received within 48 hours of collection. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Serum or plasma. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed or clotted specimens. 
Remarks
 
Stability
Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable 
Reference Interval
Interpretive Data
Refer to report.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Components
Component Test Code*Component Chart NameLOINC
2011115CBFB-MYH11 Result
2011116CBFB-MYH11/ABL1 Ratio
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases