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Eosinophil Granule Major Basic Protein, Tissue
2010921
Ordering Recommendation

Identify eosinophil involvement by staining for eosinophil granule major basic protein 1 (eMBP1) and eosinophil-derived neurotoxin (EDN) to detect both cellular localization and extracellular deposition.
Eosinophil granule proteins are toxic to tissues and cells and may be pathogenic in disease but not recognized when deposited outside of morphologically identifiable intact eosinophils.

Mnemonic
EGMBP TIS
Methodology
Immunofluorescence/Affinity Chromatography
Performed
Varies
Reported
1-3 weeks
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Tissue.  
Specimen Preparation
Transport tissue in Michel's media (ARUP supply #45462) available online through eSupply using ARUP Connect or call ARUP Client Services at (800) 522-2787. Also acceptable: Zeus tissue fixative.  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 10 days; Refrigerated: 10 days; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data


Note
CPT Code(s)
88305; 88342
Components
Component Test Code*Component Chart NameLOINC
0097167SO Source31208-2
2010911EER Eosinophil Granule MBP in Tissues
2010922Eosinophil Granule MBP in Tissues
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases

Performed at UUHC-Immunodermatology