Ordering Recommendation

Confirm presence of disease; not recommended for initial testing.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Remove serum from cells ASAP or within 2 hours of collection. Transfer 2.5 mL serum to an ARUP Standard Transport Tube. (Min: 1.5 mL) Parallel testing is preferred and
convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated or heat-inactivated specimens.

Remarks

Mark specimens plainly as acute or convalescent.

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Semi-Quantitative Agglutination/Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Immunoblot

Performed

Mon-Fri

Reported

2-5 days

Reference Interval

Test Number
Components
Reference Interval
  Brucella Ab (Total) by Agglutination Less than 1:20
  Rocky Mt Spotted Fever IgG Less than 1:64
  Rocky Mt Spotted Fever IgM Less than 1:64
  Typhus Fever Antibody, IgG Less than 1:64
  Typhus Fever Antibody, IgM Less than 1:64
  Salmonella paratyphi/typhi Abs Interp Negative

Interpretive Data

Refer to report.


Component Interpretation
Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgG Less than 1:64  Negative - No significant level of IgG antibody detected.
1:64 - 1:128  Low Positive - Presence of IgG antibody detected, suggestive of current or past infection.
1:256 or greater  Positive - Presence of IgG antibody suggestive of recent or current infection.
Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgM Less than 1:64  Negative - No significant level of IgM antibody detected.
1:64 or greater  Positive - Presence of IgM antibody detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA Less than 1:64  Negative - No significant level of IgG antibody detected.
1:64-1:128  Equivocal - Questionable presence of IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1:256 or greater  Positive - Presence of IgG antibody detected, suggestive of current or past infection.
Rickettsia typhi (Typhus Fever) Antibody, IgM by IFA Less than 1:64  Negative - No significant level of IgM antibody detected.
1:64 or greater  Positive - Presence of IgM antibody to detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86622; 86757 x4; 86768 x5

Components

Component Test Code* Component Chart Name LOINC
0050135 Brucella Ab (Total) by Agglutination 19053-8
0050369 Rocky Mt Spotted Fever IgG 5307-4
0050372 Rocky Mt Spotted Fever IgM 5308-2
0050381 Typhus Fever Antibody, IgG 5324-9
0050383 Typhus Fever Antibody, IgM 5325-6
2010807 Salmonella paratyphi/typhi Abs Interp 17562-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Brucella Ab (Total) by Agglutination
  • Rocky Mt Spotted Fever IgG
  • Rocky Mt Spotted Fever IgM
  • Salmonella Typhi H Type A
  • Salmonella Typhi H Type B
  • Salmonella Typhi H Type D
  • Salmonella Typhi O Type D
  • Salmonella Typhi O Type VI
  • Typhus Fever Antibody, IgG
  • Typhus Fever Antibody, IgM
Febrile Antibodies Identification Panel