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Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor Resistance, GenoSure (Temporary Delay as of 4/28/2016 - no referral available)
2010647
Ordering Recommendation
Recommended testing for HCV genotype 1 patients prior to initiating simeprevir therapy.
Mnemonic
HCV NS3
Methodology
Polymerase Chain Reaction/Sequencing
Performed
Varies
Reported
7-13 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or plasma preparation tube (PPT).  
Specimen Preparation
Separate plasma from cells within 6 hours of collection. Transfer 3 mL plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 3 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen at -20°C: 2 weeks; Frozen at -70°C: Indefinitely   
Reference Interval
By report
Interpretive Data


Note
Provide the patients HCV genotype (subtype) 1a or 1b. Procedure should be used for patients with HCV genotype (subtype) 1a or 1b and a viral load greater than 2000 IU/mL.
CPT Code(s)
87900; 87902
Components
Component Test Code*Component Chart NameLOINC
2010648EER HCV NS3/4A, Genosure
2010649Hepatitis C Virus (HCV) Genotype
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Q80K Polymorphism

Performed at Monogram Biosciences