Ethosuximide, Serum or Plasma
2010358
Ordering Recommendation
 
Mnemonic
ETHOSUX
Methodology
Quantitative Enzyme Immunoassay
Performed
Tue, Wed, Sat
Reported
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.  
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).  
Remarks
  
Stability
After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 2 months  
Reference Interval
 
 
Test Number Components Reference Interval
 Ethosuximide Therapeutic: 40-​100 µg/mL
Toxic: > 150 µg/mL
Interpretive Data
The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Toxic concentrations may cause dizziness, drowsiness and anorexia. The incidence of adverse reactions is low; however, life-threatening agranulocytosis and fatal pancytopenia have been reported.  
Note
 
CPT Code(s)
80168
Components
Component Test Code*Component Chart NameLOINC
0090415Ethosuximide3616-0
2010130Ethosuximide Dose Information4245-7
2010131Ethosuximide Draw Time49049-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Zarontin