Hypoglycemia Panel, Sulfonylureas Qualitative, Serum or Plasma
Ordering Recommendation
Preferred test for evaluating if etiology of hypoglycemia is sulfonylurea ingestion.
Qualitative Liquid Chromatography-Tandem Mass Spectrometry
Wed, Sun
1-6 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Plain red, gray (NaF/K Oxalate), green (Na Heparin), lavender (EDTA), or pink (K2EDTA).  
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.4 mL)  
Storage/Transport Temperature
Frozen. Also acceptable: Refrigerated.  
Unacceptable Conditions
Separator tubes.  
Ambient: 48 hours; Refrigerated: 11 days; Frozen: 3 months  
Reference Interval
Available Separately Drug Cutoff Concentration
No Glyburide 5 ng/mL
No Glimepiride 5 ng/mL
No Glipizide 5 ng/mL
No Repaglinide 5 ng/mL
No Nateglinide 5 ng/mL
No Acetohexamide 100 ng/mL
No Chlorpropamide 100 ng/mL
No Tolazamide 100 ng/mL
No Tolbutamide 100 ng/mL
Interpretive Data
This assay is used to evaluate hypoglycemia that may be caused from the ingestion of sulfonylurea drugs. Hypoglycemic drugs are detected (present) in this assay if the drug concentration is greater than the limit of detection (cut-off). The presence of hypoglycemic drug(s) indicates a recent ingestion.  
CPT Code(s)
Component Test Code*Component Chart NameLOINC
2010293Tolbutamide, Serum/Plasma21567-3
2010294Tolazamide, Serum/Plasma21566-5
2010295Repaglinide, Serum/Plasma48328-9
2010296Nateglinide, Serum/Plasma49487-2
2010297Glyburide, Serum/Plasma48327-1
2010298Glipizide, Serum/Plasma48326-3
2010299Glimepiride, Serum/Plasma48325-5
2010300Chlorpropamide, Serum/Plasma48329-7
2010301Acetohexamide, Serum/Plasma43626-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Diabinese® (Sulfonylurea Hypoglycemics Panel (Qualitative), Serum or Plasma)