Severe Combined Immunodeficiency (SCID) Panel, Sequencing and Deletion/Duplication, 19 Genes
2010219
Ordering Recommendation
Preferred test for individuals with
•Clinical phenotype of SCID, Omenn syndrome or other combined immunodeficiency disorders
•Abnormal newborn screen T-cell receptor excision circles (TREC) test result suggestive of SCID
Mnemonic
SCID PAN
Methodology
Massive Parallel Sequencing/Exonic Oligonucleotide-based CGH Microarray
Performed
Varies
Reported
6-8 weeks
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or yellow (ACD Solution A or B).  
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
Refer to report.



Counseling and informed consent are recommended for genetic testing. Consent forms are available online at www.aruplab.com.

See Compliance Statement C: www.aruplab.com/CS
Note
CPT Code(s)
81405 (IL2RG), 81479 x2
Components
Component Test Code*Component Chart Name
2010220SCID Panel Specimen
2010223SCID Panel Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • ADA, AK2/ADK2, CD247, CD3Z, CD3D, CD3E, CORO1A, DCLRE1C/ARTEMIS, FOXN1/WHN, IL2RG
  • IL7R, JAK3, LIG4, NHEJ1, PNP, PRKDC/DNA-PKcs, PTPRC/CD45, RAG1, RAG2, RMRP