RUNX1-RUNX1T1 (AML1-ETO) t(8;21) Detection, Quantitative
2010138
Ordering Recommendation
Detect and quantitate RUNX1-RUNX1T1 fusions arising from t(8;21) in acute myeloid leukemia (AML).
Mnemonic
AML1-ETO Q
Methodology
Quantitative Reverse Transcription Polymerase Chain Reaction
Performed
RNA isolation: Sun-Sat
Assay: Varies
Reported
5-7 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) or bone marrow (EDTA).  
Specimen Preparation
Transport 5 mL whole blood. (Min: 1 mL) OR Transport 3 mL bone marrow. (Min: 1 mL) Specimens must be received within 48 hours of collection due to lability of RNA.  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Serum or plasma. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed, or clotted specimens.  
Remarks
  
Stability
Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
Refer to report.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
81401
Components
Component Test Code*Component Chart NameLOINC
2010139RUNX1-RUNX1T1 Result21819-8
2010140RUNX1-RUNX1T1/ABL1 Ratio21793-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • t(8;21) (RUNX1-RUNX1T1 (AML1-ETO) t(8;21) Detection, Quantitative)