Phosphatidylserine and Prothrombin Antibodies, IgG and IgM
2009451
Ordering Recommendation
May be useful as an independent risk marker for thrombosis associated with APS and related diseases. Consider using when all criteria aPL antibody tests are negative; positive results should be reported to document persistence.
Mnemonic
APS/PT PAN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Thu
Reported
1-8 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube. Also acceptable: Blue (sodium citrate).  
Specimen Preparation
Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.15 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Other body fluids. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
 
 
Available
Separately
Component Reference Interval
2009448 Phosphatidylserine and Prothrombin IgG 0-​30 Units
No Phosphatidylserine and Prothrombin IgM 0-​30 Units
Interpretive Data
The presence of elevated and persistent aPS/PT IgG and IgM antibodies (with or without lupus anticoagulant activity) may serve as a risk marker of thrombotic events in patients with certain autoimmune diseases, including antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). Strong clinical correlation is recommended for isolated IgM aPS/PT antibody.  
Note
 
CPT Code(s)
83516 x2
Components
Component Test Code*Component Chart NameLOINC
2009448Phosphatidylserine and Prothrombin IgG 
2009450Phosphatidylserine and Prothrombin IgM 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases