HIV1 Genotype and Integrase Inhibitor Resistance by Sequencing
Ordering Recommendation

HIV-1 genotyping provides antiretroviral susceptibility information for
• Protease inhibitors (PI)
• Reverse transcriptase inhibitors (NRTI, NNRTI)
• Integrase inhibitors (INI)
Intended for patients with viral load >1000 copies/mL.

Polymerase Chain Reaction/Sequencing
7-10 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Lavender (EDTA), pink (K2EDTA) or plasma preparation tube.  
Specimen Preparation
Separate plasma from cells within 6 hours. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 3 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Serum. Heparinized specimens.  
Please submit most recent viral load and test date, if available.  
On Cells: Ambient: 6 hours; After separation from Cells: Ambient 24 hours; Refrigerated: 5 days; Frozen: 4 months  
Reference Interval
Available ComponentsReference Interval
Yes (0055670)Human Immunodeficiency Virus 1, Genotype by SequencingRefer to report
Yes (2004457)HIV-1 Integrase Inhibitor Resistance by SequencingRefer to report

Interpretive Data
Refer to individual components.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
This test may be unsuccessful if the plasma HIV-1 RNA viral load is less than 1,000 HIV-1 RNA copies per mL of plasma.
CPT Code(s)
87901; 87906
Component Test Code*Component Chart NameLOINC
0051722HIV-1 Genotype by Sequencing53798-5
2004458HIV-1 Integrase Inhib. Resistance, Seq72560-6
2010245EER HIV-1 Genotype by Seq for Panel11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • HIV Genotype (Human Immunodeficiency Virus 1, Genotyping), Raltegravir (Isentress) Resistance (HIV-1 Integrase Inhibitor Resistance by Sequencing)