Meningoencephalitis Panel with Reflex to Herpes Simplex Virus Types 1 and 2 Glycoprotein G-Specific Antibodies, IgG, CSF
2008917
 
Ordering Recommendation
Mnemonic
MENING CSF
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
2-6 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory.
Specimen Required
Patient Preparation
 
Collect
CSF.  
Specimen Preparation
Transfer 3 mL CSF to an ARUP Standard Transport Tube. (Min: 1.2 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Serum or plasma. Contaminated or heat-inactivated specimens.  
Remarks
 
Stability
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
0098893California Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098898California Encephalitis Antibody, IgM by IFA, CSF Less than 1:1
0098896Eastern Equine Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098729Eastern Equine Encephalitis Antibody, IgM by IFA, CSF Less than 1:1
0098895St. Louis Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098899St. Louis Encephalitis Antibody, IgM by IFA, CSF Less than 1:1
0098897Western Equine Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098730Western Equine Encephalitis, Antibody, IgM by IFA, CSF Less than 1:1
0050238West Nile Virus Antibody, IgG by ELISA, CSF 1.29 IV or less: Negative -​ No significant level of West Nile virus IgG antibody detected.
1.30-​1.49 IV: Equivocal -​ Questionable presence of West Nile virus IgG antibody detected. Repeat testing in 10-​14 days may be helpful.
1.50 IV or greater: Positive -​ Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection.
0050239West Nile Virus Antibody, IgM by ELISA, CSF 0.89 IV or less: Negative -​ No significant level of West Nile virus IgM antibody detected.
0.90-​1.10 IV: Equivocal -​ Questionable presence of West Nile virus IgM antibody detected. Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ Presence of IgM antibody to West Nile virus detected, suggestive of current or recent infection.
0054440Measles (Rubeola) Antibody, IgG, CSF Effective August 20, 2012

24.9 AU/mL or less: Negative -​ No significant level of IgG antibody to measles (rubeola) virus detected.
25.0-​29.9 AU/mL: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
30.0 AU/mL or greater: Positive -​ IgG antibody to measles (rubeola) detected, which may indicate a current or past measles (rubeola) infection.
0054441Measles (Rubeola) Antibody, IgM, CSF 0.79 AU or less: Negative -​ No significant level of IgM antibodies to measles (rubeola) virus detected.
0.80-​1.20 AU: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
1.21 AU or greater: Positive -​ IgM antibodies to measles (rubeola) virus detected. Suggestive of current or recent infection or immunization. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection or immunization.
0054442Mumps Virus Antibody IgG, CSF Effective August 20, 2012

8.9 AU/mL or less: Negative -​ No significant level of detectable IgG mumps virus antibody.
9.0-​10.9 AU/mL: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
11.0 AU/mL or greater: Positive -​ IgG antibody to mumps virus detected, which may indicate a current or past mumps virus infection.
0054443Mumps Virus Antibody IgM, CSF 0.79 IV or less: Negative -​ No significant level of detectable IgM antibody to Mumps virus.
0.80-​1.20 IV: Equivocal -​ Borderline levels of IgM antibody to Mumps virus. Repeat testing in 10-​14 days may be helpful.
1.21 IV or greater: Positive -​ Presence of IgM antibody to Mumps virus detected, which may indicate a current or recent infection. However, low levels of IgM antibody may occasionally persist for more than 12 months post-​infection or immunization.
0054444Varicella-​Zoster Virus Antibody, IgG, CSF Effective August 20, 2012

134 IV or less: Negative -​ No significant level of IgG antibody to varicella-​zoster virus detected.
135-​165 IV: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
166 IV or greater: Positive -​ IgG antibody to varicella-​zoster virus detected, which may indicate a current or past varicella-​zoster infection.
0054445Varicella-​Zoster Virus Antibody, IgM by ELISA (CSF) 0.90 ISR or less: Negative -​ No significant level of IgM antibody to varicella-​zoster virus detected.
0.91-​1.09 ISR: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
1.10 ISR or greater: Positive -​ Significant level of IgM antibody to varicella-​zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
0050408Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA, CSF 0.89 IV or less: Negative -​ No significant level of detectable HSV IgM antibody.
0.90-​1.09 IV: Equivocal -​ Questionable presence of IgM antibodies. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater: Positive -​ IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
0050394Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG, CSF 0.89 IV or less: Negative -​ No significant level of detectable HSV IgG antibody.
0.90-​1.09 IV: Equivocal -​ Questionable presence of IgG antibodies. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater: Positive -​ IgG antibody to HSV detected which may indicate a current or past HSV infection.
0050379Herpes Simplex Virus Type 1 Glycoprotein G-​Specific Antibody, IgG by ELISA, CSF 0.89 IV or less: Negative -​ No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.90-​1.10 IV: Equivocal -​ Questionable presence of IgG antibody to HSV type 1. Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past infection.
0050359Herpes Simplex Virus Type 2 Glycoprotein G-​Specific Antibody, IgG by ELISA, CSF 0.89 IV or less: Negative -​ No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.90-​1.10 IV: Equivocal -​ Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
Interpretive Data
Refer to individual components for additional Interpretive Data.

See Compliance Statement B: www.aruplab.com/CS
Note
If HSV 1 and/or 2 IgG, CSF is 1.10 IV or greater, then HSV 1 gG-Specific IgG, CSF and HSV 2 gG-Specific IgG, CSF will be added. Additional charges apply.
CPT Code(s)
86651 x2; 86652 x2; 86653 x2; 86654 x2; 86789; 86788; 86765 x2; 86735 x2; 86787 x2; 86694; 86694; if reflexed, add 86695; 86696
Components
Component Test Code*Component Chart Name
0050238West Nile Virus Antibody IgG CSF
0050239West Nile Virus Antibody IgM CSF
0050394HSV 1/2 Antibody Screen IgG, CSF
0050408HSV 1 and/or 2 Antibodies IgM, CSF
0054440Measles, Rubeola, Antibody IgG CSF
0054441Measles, Rubeola, Antibody IgM CSF
0054442Mumps Virus Antibody IgG CSF
0054443Mumps Virus Antibody IgM CSF
0054444VZV Antibody IgG CSF
0054445VZV Antibody IgM CSF
0098729Eastern Equine Enceph Ab, IgM, CSF
0098730Western Equine Enceph Ab, IgM, CSF
0098893California Encephalitis IgG CSF
0098895St. Louis Encephalitis Ab, IgG, CSF
0098896Eastern Equine Enceph Ab, IgG, CSF
0098897Western Equine Enceph Ab, IgG, CSF
0098898California Encephalitis IgM CSF
0098899St. Louis Encephalitis Ab, IgM, CSF
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References