CD57+ NK Cells, Peripheral Blood by Flow Cytometry
Ordering Recommendation

Identifies and quantifies CD57+/CD3- NK cells.

Flow Cytometry
1-3 days
1-3 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin). 
Specimen Preparation
Transport 4 mL whole blood. (Min: 0.5 mL) Specimens must be analyzed within 72 hours of collection. 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. 
Unacceptable Conditions
Specimens older than 72 hours. Clotted or hemolyzed specimens. 
Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable 
Reference Interval
Available Separately
Reference Interval
NoPercent CD57+CD3- (NK Cells)1-16 percent of lymph
NoAbs CD57+CD3- (NK Cells)21-357 cells/µL

Interpretive Data
This test identifies and quantifies the CD57+/CD3- NK cells. The significance of low CD57+NK values in diagnosing and monitoring chronic Lyme disease is not well established and should be used in conjunction with other diagnostic tests specified in the Centers for Disease Control Lyme Disease case definition.

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Component Test Code*Component Chart NameLOINC
2008913% CD57+CD3- (NK Cells)51286-3
2008914Abs CD57+CD3- (NK Cells)50640-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.