Lung Cancer Panel
2008894
 
Ordering Recommendation
Screening panel to determine eligibility for TKIs. EGFR, ALK, and ROS1 genes tested; EGFR by Pyrosequencing and ALK and ROS1 by IHC. To include KRAS by PCR, refer to Lung Cancer Panel with KRAS 2008895.
Mnemonic
LUNG PANEL
Methodology
Polymerase Chain Reaction/Pyrosequencing/Immunohistochemistry
Performed
Varies
Reported
12-14 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Tumor tissue.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or 13 unstained 5-micron slides (8 on positively charged slides AND 5 on uncharged slides). (Min: 9 slides: 5 positively charged AND 4 uncharged) Tissue block will be returned after testing. Transport block and/or slide(s) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Less than 25 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives. Decalcified specimens.  
Remarks
Include surgical pathology report.  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
Interpretive Data
Refer to report.

See Compliance Statement A: www.aruplab.com/CS
Note
CPT Code(s)
88381, 81235, 88360 x2, if reflexed add 88368 x2
Components
Component Test Code*Component Chart Name
2002148Block ID
2002442EGFR by Pyrosequencing
2007325ALK(D5F3) by IHC Reference Number
2007326ALK(D5F3) by IHC Pct of Tumor Staining
2007327ALK(D5F3) by IHC Result
2008415ROS1 by IHC Result
2008417ROS1 Client Block ID
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References