Expanded Hearing Loss Panel, Sequencing (56 Genes)
2008800
Ordering Recommendation
May be ordered as first-tier genetic test for hearing loss, or after GJB2, GJB6, and mitochondrial mutation testing has been performed.
Mnemonic
EHL SEQ
Methodology
Massive Parallel Sequencing
Performed
Varies
Reported
10-12 weeks  
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) or yellow (ACD Solution A or B).  
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
  
Remarks
Submit the Patient History Form for Expanded Hearing Loss with the Electronic Packing List.  
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable  
Reference Interval
By report  
Interpretive Data
Refer to report.



Counseling and informed consent are recommended for genetic testing. Consent forms are available online at www.aruplab.com.

See Compliance Statement C: www.aruplab.com/CS  
Note
 
CPT Code(s)
81252 (GJB2), 81254 (GJB6), 81404 x2 (CLRN1, USH1G), 81405(DFNB59), 81406 (SLC26A4), 81407 x3 (MYO7A, PCDH15, USH1C), 81408 x2 (CDH23, USH2A), 81479
Components
Component Test Code*Component Chart Name
2008801Expanded Hearing Loss Seq Specimen
2008802Expanded Hearing Loss Sequencing Interp
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 0051374 Connexin 26 (GJB2) Sequencing
  • 2001956 Hearing Loss, Nonsyndromic, Connexin 30 (GJB6) 2 Deletions
  • 2001992 Hearing Loss, Nonsyndromic Panel (GJB2) Sequencing, (GJB2) 2 Deletions and Mitochondrial DNA 2 Mutations
  • ACTG1, CCDC50, CDH23, CEACAM16, CLDN14, CLRN1, COCH, COL11A2, CRYM, DFNA5, DFNB31, DIAPH1, DNMT1
  • DSPP, ESPN, ESRRB, EYA4, GJB2, GJB3, GJB6, GPR98, GPSM2, GRHL2, HARS2
  • HSD17B4, KCNQ4, LHFPL5, MARVELD2, MASP1, MYH14, MYH9, MYO15A, MYO1A, MYO3A, MYO6, MYO7A, OTOA, OTOF
  • PCDH15, PJVK, POU4F3, RDX, SLC26A4, SLC26A5, SMPX, STRC, TECTA, TMC1, TMIE, TMPRSS3, TPRN, TRIOBP
  • USH1C, USH1G, USH2A, WFS1
  • Usher syndrome
  • Wolfram syndrome