1p/19q Deletion by FISH
Ordering Recommendation

Use to diagnose oligodendroglioma brain tumors; indicated in both low-grade and high-grade (anaplastic) oligodendrogliomas. Predict response to therapy in oligodendrogliomas.

Fluorescence in situ Hybridization
3-7 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Tumor tissue.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect paraffin block from excessive heat. Transport block or 6 unstained (4 micron thick sections) positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect or contact ARUP Client Services at (800) 522-2787 (kit recommended but not necessary). (Min 3 slides)  
Storage/Transport Temperature
Room temperature or refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.  
Include surgical pathology report.  
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
Refer to report.

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.
CPT Code(s)
88377 x2
Component Test Code*Component Chart NameLOINC
20085201p19q by FISH42634-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • 1p deletion FISH
  • 1p,1q codeletion FISH
  • 1p/19q Deletion
  • 1p/19q Deletion in Gliomas, FISH, Tissue
  • 1p/19q deletion in Oligodendroglioma
  • 1p/19q FISH
  • 1p/19q in oligodendrogliomas
  • 1q deletion FISH
  • Chromosome Analysis by FISH for 1p/19q Deletion in Gliomas
  • FISH for 1p/19q Deletion in Gliomas
  • LOH (Loss of Heterozygosity) 1p/19q in Gliomas
  • Loss of Heterozygosity (LOH) 1p/19q in Gliomas