T-Cell Clonality by Next Generation Sequencing
2008409
Ordering Recommendation
Diagnosis and monitoring of T-cell lymphoproliferative disorders.
Mnemonic
TCRG NGS
Methodology
Massive Parallel Sequencing
Performed
Sun, Tue, Thu
Reported
7-10 days  
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Whole blood: Lavender (EDTA). OR Bone marrow: EDTA. OR Tissue.  
Specimen Preparation
Whole blood: Transport 5 mL whole blood. (Min: 1 mL)
OR Bone marrow:
Transport 3 mL bone marrow. (Min: 1 mL)
OR Fresh tissue:
Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue.
OR FFPE tumor tissue:
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing. Transport tissue (frozen or paraffin) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Whole blood OR Bone marrow: Refrigerated.  
Fresh tissue:
Frozen on dry ice.
FFPE tumor tissue:
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Serum. Frozen whole blood or bone marrow. Clotted or grossly hemolyzed specimens. Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.  
Remarks
  
Stability
Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue:
Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue:
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
Refer to report.



See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
81342
Components
Component Test Code*Component Chart NameLOINC
2008410T-Cell Clonality Specimen Source31208-2
2008411T-Cell Clonality Interpretation21753-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • T Cell Gamma
  • T Cell Gene Rearrangement
  • T-cell receptor gamma rearrangement
  • T-Cell Receptor Gene Rearrangement
  • tcell clonality
  • Tcell next gen
  • TCRG