T-Cell Clonality by Next Generation Sequencing
2008409
 
Ordering Recommendation
Diagnosis and monitoring of T-cell lymphoproliferative disorders.
Mnemonic
TCRG NGS
Methodology
Massive Parallel Sequencing
Performed
Sun, Tue, Thu
Reported
7-10 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory.
Specimen Required
Patient Preparation
 
Collect
Whole blood: Lavender (EDTA). OR Bone marrow: EDTA. OR Tissue.  
Specimen Preparation
Whole blood: Transport 5 mL whole blood. (Min: 1 mL)
OR Bone marrow:
Transport 3 mL bone marrow. (Min: 1 mL)
OR Fresh tissue:
Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue.
OR FFPE tumor tissue:
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing. Transport tissue (frozen or paraffin) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Whole blood OR Bone marrow: Refrigerated.
Fresh tissue:
Frozen on dry ice.
FFPE tumor tissue:
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Serum. Frozen whole blood or bone marrow. Clotted or grossly hemolyzed specimens. Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.  
Remarks
 
Stability
Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue:
Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue:
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
Interpretive Data
Refer to report.



See Compliance Statement B: www.aruplab.com/CS
Note
CPT Code(s)
81342
Components
Component Test Code*Component Chart Name
2008410T-Cell Clonality Specimen Source
2008411T-Cell Clonality Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References