Hexosaminidase A Percent and Total Hexosaminidase in Leukocytes
2008125
 
Ordering Recommendation
Mnemonic
HEXOA LEUK
Methodology
Quantitative Fluorometry
Performed
Tue
Reported
2-9 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory.
Specimen Required
Patient Preparation
 
Collect
Yellow (ACD).  
Specimen Preparation
Do not transfer whole blood to other containers. Transport 3 mL whole blood. (Min: 1.0 mL)  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated.  
Unacceptable Conditions
Whole blood received greater than 3 days from collection. Grossly hemolyzed specimens.  
Remarks
Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g.TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at http://www.aruplab.com/patienthistory or by contacting ARUP Client Services.  
Stability
Ambient: 3 days; Refrigerated: 3 days; Frozen: Unacceptable  
Reference Interval
Effective November 18, 2013

Greater than or equal to 63 percent
Interpretive Data
Refer to report.
Note
This test is used for the diagnosis of Tay-Sachs disease and can also be used to identify carriers for this disorder. Carrier screening is offered to individuals of Ashkenazi Jewish descent because of the high incidence of the disease in this population.
CPT Code(s)
83080
Components
Component Test Code*Component Chart Name
2008126Hexosaminidase A Percent in Leukocytes
2008127Hexosaminidase Total, Leukocytes
2008128Hexosaminidase in Leukocytes Interp
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • HEXA enzyme testing
  • Hexosaminidase A and Total, leukocytes