Specimens from New York clients will be sent out to a New York DOH approved laboratory.
This test is used for the diagnosis of Tay-Sachs disease and can also be used to identify carriers for this disorder. Carrier screening is offered to individuals of Ashkenazi Jewish descent because of the high incidence of the disease in this population. Pregnant women or women using oral contraceptives cannot be tested using plasma or serum because of high false-positives rates. In serum samples, false positives can also be caused by several other conditions, including severe liver disease and autoimmune diseases. Testing in leukocytes should be used in these cases.