Hexosaminidase A Percent and Total Hexosaminidase, Plasma or Serum
HEXOS A P/S
New York DOH Approval Status
This test will be sent out to a New York DOH approved laboratory.
- Patient Preparation
- Yellow (ACD). Also acceptable: Plain red.
- Specimen Preparation
- Do not transfer whole blood to other containers. Transport 3 mL whole blood (Min: 1 mL) or transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
- Storage/Transport Temperature
- Whole blood: Room temperature. Serum: Frozen
- Unacceptable Conditions
- Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g.TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at http://www.aruplab.com/patienthistory or by contacting ARUP Client Services.
- Whole blood: Ambient: 3 days; Refrigerated: 3 days; Frozen: Unacceptable
Serum: Ambient: 3 days; Refrigerated: 7 days; Frozen: 1 month
|Available Separately||Components||Reference Interval|
|No||Hexosaminidase A Percent||55-76 percent|
|No||Hexosaminidase Total||800-1400 nmol hydrolyzed/hr/mL|
Refer to report.
This test is used for the diagnosis of Tay-Sachs disease and can also be used to identify carriers for this disorder. Carrier screening is offered to individuals of Ashkenazi Jewish descent because of the high incidence of the disease in this population. Pregnant women or women using oral contraceptives cannot be tested using plasma or serum because of high false-positives rates. In serum samples, false positives can also be caused by several other conditions, including severe liver disease and autoimmune diseases. Testing in leukocytes should be used in these cases.
|Component Test Code*||Component Chart Name|
|2008123||Hexosaminidase A Percent|
|2008124||Hexosaminidase Plasma/Serum Interp|