Solid Tumor Mutation Panel by Next Generation Sequencing
2007991
Ordering Recommendation
Predicts prognosis and therapeutic response in patients with solid tumor cancers.
Mnemonic
SOLID NGS
Methodology
Massively Parallel Sequencing
Performed
Varies
Reported
12-14 days  
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Tumor tissue.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport block and/or slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Resections:
8 unstained 5-micron slides. (Min: 5 slides)
Small biopsies
: 15 unstained 5-micron slides. (Min: 10 slides)  
Storage/Transport Temperature
Room temperature. Ship in cooled container during summer months.  
Unacceptable Conditions
Less than 10 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives. Decalcified specimens.  
Remarks
Include surgical pathology report.  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
Refer to report.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
81210  (BRAF), 81235  (EGFR), 81275  (KRAS), 81310  (NPM1), 81402  (MPL), 81403 x6  (ABL1; CTNNB1; HRAS; IDH1; IDH2;KRAS), 81404 x6  ( FGFR2; FGFR3; KIT; NRAS; PDGFRA; RET), 81405  (TP53), 81479; 88381
Components
Component Test Code*Component Chart NameLOINC
2007992Solid Tumor Panel by NGS Block ID 
2007993Solid Tumor Panel By NGS Interpretation 
2008147EER Solid Tumor Panel by NGS 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Solid Tumor Nex Gen sequencing