Paraneoplastic Antibodies (PCCA/ANNA) by IFA with Reflex to Titer and Western Blot
2007961
 
Ordering Recommendation
Mnemonic
PCCA/ANNA
Methodology
Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Western Blot
Performed
Wed
Reported
1-9 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.75 mL)  
Storage/Transport Temperature
Refrigerated  
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
Purkinje Cell/Neuronal Nuclear IgG Scrn None Detected
Neuronal Nuclear Antibody (ANNA) IFA Titer, IgG Less than 1:10
Purkinje Cell Antibody, Titer Less than 1:10
2007963Neuronal Nuclear (Hu, Ri, and Yo) Antibodies IgG by Western Blot None Detected
Interpretive Data


See Compliance Statement D: www.aruplab.com/CS
Note
PCCA/ANNA antibodies are screened by IFA. If the IFA screen is positive at 1:10, then a specific titer (PCCA or ANNA) and Western Blot will be added. Additional charges apply
CPT Code(s)
86255; if reflexed add 86256 and 83516
Components
Component Test Code*Component Chart Name
2007962Purkinje Cell/Neuronal Nuclear IgG Scrn
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • ANNA
  • ANNA-1
  • ANNA-2
  • Anti Ri
  • Anti-Hu
  • Anti-Yo
  • Antinuclear neuronal Ab
  • Neuronal Nuclear Antibody
  • Paraneoplastic Ab screen
  • Paraneoplastic Autoantibody Western Blot Confirmation, Paraneoplastic Neurological Autoimmunity
  • PCA-1
  • Purkinje Cell Cytoplasmic Antibodies