ERBB2 (HER2) (4B5) by Immunohistochemistry
2007329
 
Immunohistochemistry Stain Form Recommended  (ARUP form #32978)Immunohistochemistry Stain Form Recommended (ARUP form #32978)
Ordering Recommendation
Mnemonic
4B5 IHC
Methodology
Immunohistochemistry
Performed
Mon-Fri
Reported
1-3 days
N/A
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Tissue or cells.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5- micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)522-2787. (Min: 2 slides) If sending precut slides, do not oven bake.  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Specimens submitted with non-representative tissue type. Depleted specimens.  
Remarks
IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services at (800)522-2787.  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
Interpretive Data
Note
This test code is handled as "Stain and Return." For stain with interpretation, refer to ERBB2 (HER2/neu) (4B5) with Interpretation by Immunohistochemistry (ARUP test code 2002218). To request a consultation, submit the pathology report, all associated case materials (clinical history, blocks, slides, etc.) with the Anatomic Pathology requisition form (form #32960) in place of the Immunohistochemistry form.
CPT Code(s)
88360
Components
Component Test Code*Component Chart Name
2007330ERBB2 (Her2) (4B5) IHC Reference Number
2007331ERBB2 (Her2) (4B5) IHC Result
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • 4B5 IHC HER2
  • c-erbB2 IHC
  • ERBB2 (4B5) IHC
  • HER-2/neu (4B5) IHC
  • PATHWAY® anti-HER-2/neu (4B5) by Immunohistochemistry, ERBB2, Herceptin