SS18 (SYT) (18q11) Gene Rearrangement by FISH
2007222
Ordering Recommendation
Molecular diagnosis of synovial sarcoma.
Mnemonic
SYT FISH
Methodology
Fluorescence in situ Hybridization
Performed
Varies
Reported
4-12 days  
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Tumor tissue.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin-embed tissue. Transport tissue block or 5 unstained 5-micron slides. (Min: 3 slides) Protect paraffin block from excessive heat. Transport block(s) and/or slide(s) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Frozen specimens. Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.  
Remarks
Include surgical pathology report.  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
By report  
Interpretive Data
Refer to report.

See Compliance Statement A: www.aruplab.com/CS  
Note
 
CPT Code(s)
88367
Components
Component Test Code*Component Chart Name
0049380SS18 (SYT) by FISH
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 18q11 gene rearrangement
  • 18q11.2
  • SS18 Break Apart FISH
  • SS18 FISH
  • SS18 translocation FISH
  • SYT FISH
  • SYT translocation FISH