Cotinine Screen, Urine
2007081
Ordering Recommendation
Assess active exposure to nicotine and compliance with smoking-cessation programs.
Mnemonic
COTININE
Methodology
Enzyme Multiplied Immunoassay Technique
Performed
Mon, Wed, Fri
Reported
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Random urine  
Specimen Preparation
Transfer 4 mL urine with no additives to an ARUP Standard Transport Tube. (Min: 2 mL)  
Storage/Transport Temperature
Refrigerated  
Unacceptable Conditions
Specimens exposed to repeated freeze/thaw cycles  
Remarks
  
Stability
Ambient: 10 days; Refrigerated: 10 days; Frozen: 8 months  
Reference Interval
Negative  
Interpretive Data
Cotinine is a metabolite of nicotine and may be detected up to seven days after nicotine exposure. The cutoff is set at 100 ng/mL to detect active exposure (smoking). This test will not distinguish between tobacco use and nicotine replacement therapy.  
Note
 
CPT Code(s)
80101
Components
Component Test Code*Component Chart NameLOINC
2007082Cotinine Screen, Urine12293-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Nicotine & Metabolites urine
  • Nicotine Metabolite