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Cotinine Screen, Urine
2007081
Ordering Recommendation

Urine screening test for determining active exposure to nicotine and compliance with smoking-cessation programs. For determination of active or passive nicotine use, or for differentiation between nicotine replacement and tobacco use, Nicotine and Metabolites, Urine, Quantitative (0092356) is preferred.

Mnemonic
COTININE
Methodology
Enzyme Multiplied Immunoassay Technique
Performed
Mon, Wed, Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Random urine 
Specimen Preparation
Transfer 4 mL urine with no additives to an ARUP Standard Transport Tube. (Min: 2 mL) 
Storage/Transport Temperature
Refrigerated 
Unacceptable Conditions
Specimens exposed to repeated freeze/thaw cycles 
Remarks
 
Stability
Ambient: 1 week; Refrigerated: 1 week; Frozen: 3 months 
Reference Interval
Negative
Interpretive Data
Cotinine is a metabolite of nicotine and may be detected up to seven days after nicotine exposure. The cutoff is set at 100 ng/mL to detect active exposure (smoking). This test will not distinguish between tobacco use and nicotine replacement therapy.

Note
CPT Code(s)
80302 (Alt code: G0479)
Components
Component Test Code*Component Chart NameLOINC
2007082Cotinine, Urn, Screen12293-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Nicotine & Metabolites urine
  • Nicotine Metabolite